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This product is a 62.7 kDa Human AMHR2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alternative Names
AMHR2; AMHR; MRII; MISR2; MISRII; anti-Muellerian hormone type-2 receptor; AMH type II receptor; MIS type II receptor; Muellerian inhibiting substance type II receptor; Mullerian inhibiting substance type II receptor; anti-Muellerian hormone type II receptor; anti-Mullerian hormone receptor, type II; Anti-Mullerian hormone receptor type 2