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Magic™ Membrane Protein Human AREG (Amphiregulin) Full Length (CAT#: MPC3977K) Made to Order

This product is a made-to-order Human AREG membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • AREG
  • Protein Length
  • Full length
  • Protein Class
  • Growth factor
  • TMD
  • 1
  • Sequence
  • MRAPLLPPAPVVLSLLILGSGHYAAGLDLNDTYSGKREPFSGDHSADGFE
    VTSRSEMSSGSEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDD
    SVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEF
    QNFCIHGECKYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSKIA
    LAAIAAFMSAVILTAVAVITVQLRRQYVRKYEGEAEERKKLRQENGNVHA
    IA

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • AREG
  • Full Name
  • Amphiregulin
  • Introduction
  • The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
  • Alternative Names
  • AREG; AR; SDGF; AREGB; CRDGF; amphiregulin B; colorectum cell-derived growth factor; schwannoma-derived growth factor; Amphiregulin

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