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Magic™ Membrane Protein Human ASAH2 (N-acylsphingosine amidohydrolase 2) Full Length (CAT#: MPC2115K) Made to Order

This product is a 85.5 kDa Human ASAH2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ASAH2
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 85.5 kDa
  • TMD
  • 1
  • Sequence
  • MAKRTFSNLETFLIFLLVMMSAITVALLSLLFITSGTIENHKDLGGHFFS
    TTQSPPATQGSTAAQRSTATQHSTATQSSTATQTSPVPLTPESPLFQNFS
    GYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGS
    NRTVFVSIDIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPA
    GYFQYTVFVIASEGFSNQTFQHMVTGILKSIDIAHTNMKPGKIFINKGNV
    DGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVDLNGDDLGLISWF
    AIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGPFVAAFASSNL
    GDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIAKGPGQDMFDSTQII
    GRAMYQRAKELYASASQEVTGPLASAHQWVDMTDVTVWLNSTHASKTCKP
    ALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHK
    PKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLR
    EAVQAEFASHGMQNMTVVISGLCNVYTHYITTYEEYQAQRYEAASTIYGP
    HTLSAYIQLFRNLAKAIATDTVANLSRGPEPPFFKQLIVPLIPSIVDRAP
    KGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQTHQTFLTVEKYE
    ATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRY
    FGHNRKQDILKPAVILSFEGTSPAFEVVTI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ASAH2
  • Full Name
  • N-acylsphingosine amidohydrolase 2
  • Introduction
  • Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730).
  • Alternative Names
  • ASAH2; HNAC1; BCDase; LCDase; NCDase; N-CDase; neutral ceramidase; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; acylsphingosine deacylase 2; mitochondrial ceramidase; neutral/alkaline ceramidase; non-lysosomal ceramidase; N-acylsphingosine amidohydrolase 2

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