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Magic™ Membrane Protein Human ASGR1 (Asialoglycoprotein receptor 1) Expressed in E.coli with 6xHis tag at the N-terminus for Antibody Discovery, Partial (68-291aa) (CAT#: MPX4237K)

Datasheet
This product is a 29.7kDa Human ASGR1 membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ASGR1
  • Protein Length
  • Partial (68-291aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 29.7kDa
  • TMD
  • 1
  • Sequence
  • EELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • ASGR1
  • Full Name
  • Asialoglycoprotein receptor 1
  • Introduction
  • This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Alternative Names
  • ASGR1; HL-1; ASGPR; ASGPR1; CLEC4H1; C-type lectin domain family 4 member H1; hepatic lectin H1; Asialoglycoprotein receptor 1

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