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Magic™ Membrane Protein Human AVPR1B (Arginine vasopressin receptor 1B) Full Length (CAT#: MPC0037K) Made to Order

This product is a 46.9 kDa Human AVPR1B membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • AVPR1B
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 46.9 kDa
  • TMD
  • 7
  • Sequence
  • MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATG
    GNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRF
    QGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQST
    YLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYL
    TWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRP
    SPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
    QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPL
    RHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGR
    PRPEESPRDLELADGEGTAETIIF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • AVPR1B
  • Full Name
  • Arginine vasopressin receptor 1B
  • Introduction
  • The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
  • Alternative Names
  • V1bR; AVPR3; AVPR V1b; AVPR V3; antidiuretic hormone receptor 1B; arginine vasopressin receptor 3; pituitary vasopressin receptor 3; vasopressin V3 receptor; AVPR1B; Arginine vasopressin receptor 1B

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