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Magic™ Membrane Protein Human BDKRB1 (Bradykinin receptor B1) Full Length (CAT#: MPC0039K) Made to Order

This product is a 40.5 kDa Human BDKRB1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BDKRB1
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 40.5 kDa
  • TMD
  • 7
  • Sequence
  • MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFF
    GLLGNLFVLLVFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQ
    FNWPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQR
    RRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHF
    ARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRCGGRKDSKTTA
    LILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
    AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLF
    WRN

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • BDKRB1
  • Full Name
  • Bradykinin receptor B1
  • Introduction
  • Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene belongs to the G-protein coupled receptor 1 family. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
  • Alternative Names
  • B1R; BKR1; B1BKR; BKB1R; BRADYB1; BK-1 receptor; bradykinin B1 receptor; bradykinin receptor 1; BDKRB1; Bradykinin receptor B1

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