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Magic™ Membrane Protein Human BMP2 (Bone morphogenetic protein 2) for Antibody Discovery (CAT#: MP0069Q)

This product is a 26.0 kDa Human BMP2 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BMP2
  • Protein Length
  • Partial
  • Protein Class
  • Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transmembrane
  • Molecular Weight
  • 26.0 kDa
  • Sequence
  • QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR

Product Description

  • Expression Systems
  • CHO
  • Endotoxin
  • < 1 EU/µg
  • Purity
  • >95% pure by SDS-PAGE gel and HPLC analyses
  • Buffer
  • Lyophilized (sterile filtered) purified protein

Target

  • Target Protein
  • BMP2
  • Full Name
  • Bone morphogenetic protein 2
  • Introduction
  • This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
  • Alternative Names
  • BDA2; BMP2A; SSFSC; bone morphogenetic protein 2; bone morphogenetic protein 2A; BMP-2; BMP-2A

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