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Magic™ Membrane Protein Human CACNG2 (Calcium voltage-gated channel auxiliary subunit gamma 2) Full Length (CAT#: MPC0438K) Made to Order

This product is a 35.9 kDa Human CACNG2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CACNG2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 35.9 kDa
  • TMD
  • 4
  • Sequence
  • MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENET
    SKKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRA
    VRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNI
    IGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHM
    FIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSR
    DASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVH
    NCIQKENKDSLHSNTANRRTTPV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • 6xHis tag at C-terminal
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CACNG2
  • Full Name
  • Calcium voltage-gated channel auxiliary subunit gamma 2
  • Introduction
  • The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. The AMPA subtype of ionotropic glutamate receptors are ligand gated ion channels that are typically activated by glutamate released from presynaptic neuron terminals and mediate fast neurotransmission in excitatory synapses. TARPs thus play an important role in synaptic plasticity, learning and memory. Mutations in this gene cause an autosomal dominant form of cognitive disability.
  • Alternative Names
  • MRD10; voltage-dependent calcium channel gamma-2 subunit; TARP gamma-2; neuronal voltage-gated calcium channel gamma-2 subunit; stargazin; transmembrane AMPAR regulatory protein gamma-2; CACNG2; Calcium voltage-gated channel auxiliary subunit gamma 2

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