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Magic™ Membrane Protein Human CD6 (CD6 molecule) Expressed in NS0 for Antibody Discovery, Partial (18-398aa) (CAT#: MPX0767K)

Datasheet
This product is a 68.2 kDa Human CD6 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD6
  • Protein Length
  • Partial (18-398aa)
  • Protein Class
  • Immunity
  • Molecular Weight
  • 68.2 kDa
  • TMD
  • 1
  • Sequence
  • HPSPAPPDQLNTSSAESELWEPGERLPVRLTNG
    SSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPP
    TPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR
    ARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCR
    QLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCG
    HKEDAGVVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAK
    VLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSWRFNNSNLC
    SQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVTVKIENKESRE

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc and 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • CD6
  • Full Name
  • CD6 molecule
  • Introduction
  • This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CD6; TP120; T-cell differentiation antigen CD6; CD6 antigen; T12; CD6 molecule

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