Magic™ Membrane Protein Human CD86 (CD86 molecule) for Antibody Discovery (CAT#: MP1481J)

Datasheet

This product is a 26.69 kDa Human CD86 membrane protein expressed in Mammalian cell. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

Host Species
Human

Target Protein
CD86

Protein Length
Partial (24-247aa)

Protein Class
Immune Checkpoints

Molecular Weight
26.69 kDa

Sequence
APLKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLLRTKNSTIEYDGVMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSIELEDPQPPPDHIP

Product Description

Activity
Validated by ELISA

Expression Systems
Mammalian cell

Tag
C-6xHis

Reconstitution
Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration).

Endotoxin
<1.0 EU/μg

Purity
>95% as determined by SDS-PAGE

Buffer
0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.2

Target

Target Protein
CD86

Full Name
CD86 molecule

Introduction
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG1 produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation.

Alternative Names
Activation B7-2 antigen 3; Activation B7-2 antigen; B-lymphocyte activation antigen B7-2 2; B-lymphocyte activation antigen B7-2; B7 2; B7; B7-2; B7.2; B70; B72; B72 antigen; BU63; CD28 antigen ligand 2 2; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen (CD28 antigen ligand 2 B7 2 antigen); CD86 antigen (CD28 antigen ligand 2; B7-2 antigen) 1; 2; CD86 antigen (CD28 antigen ligand 2; B7-2 antigen); CD86 antigen; CD86 molecule; CD86_HUMAN; CLS1; CTLA-4 counter-receptor B7.2 2; CTLA-4 counter-receptor B7.2 2; 3; CTLA-4 counter-receptor B7.2; Early T-cell costimulatory molecule 1; ETC-1; FUN 1; FUN-1; FUN1; LAB72; Ly-58; Ly58; MB7; MB7-2; Membrane glycoprotein; MGC34413; T lymphocyte activation antigen CD86 precursor; T-lymphocyte activation antigen CD86; TS/A-2

Gene ID
942

UniProt ID
P42081

Customer reviews and Q&As Write a review Ask a question

Related Products

Online Inquiry

	USA: Europe: Germany:
	Call us at: USA: UK: Germany:
	Fax:
	Email: