Magic™ Membrane Protein Human CD93 (CD93 molecule) Expressed in NS0 for Antibody Discovery, Partial (24-580aa) (CAT#: MPX0487K)

Datasheet

This product is a 84.7 kDa Human CD93 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

Host Species
Human

Target Protein
CD93

Protein Length
Partial (24-580aa)

Protein Class
Cell adhesion

Molecular Weight
84.7 kDa

Sequence
ADTEAVVCVGTACYTAHSGKLSAAEAQ
NHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQRE
KGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNSCISKRCVSLLLDLSQ
PLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVT
YTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDW
GSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTC
ASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQ
DSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGC
TNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSF
HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATA
SPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIH
HATAASGPQEPAGGDSSVATQNNDGTDGQK

Product Description

Activity
Yes

Expression Systems
NS0

Tag
hIgG1 Fc tag at the C-terminus

Protein Format
Soluble

Reconstitution
Reconstitute at 500 μg/mL in PBS.

Endotoxin
<0.10 EU per 1 μg of the protein by the LAL method.

Purity
>80%, by SDS-PAGE under reducing conditions and visualized by silver stain

Buffer
Lyophilized from a 0.2 μm filtered solution in PBS.

Target

Target Protein
CD93

Full Name
CD93 molecule

Introduction
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.

Alternative Names
CD93; C1QR1; C1qRP; CDw93; ECSM3; MXRA4; C1qR(P); dJ737E23.1; complement component C1q receptor; C1q receptor 1; C1q/MBL/SPA receptor; C1qR; CD93 antigen; complement component 1 q subcomponent receptor 1; matrix-remodeling-associated protein 4; matrix-remodelling associated 4; CD93 molecule

Gene ID
22918

UniProt ID
Q9NPY3

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