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Magic™ Membrane Protein Human CDH7 (Cadherin 7) Expressed in CHO for Antibody Discovery, Partial (1-607aa) (CAT#: MPX0306K)

This product is a 62.2 kDa Human CDH7 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CDH7
  • Protein Length
  • Partial (1-607aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 62.2 kDa
  • TMD
  • 1
  • Sequence
  • MKLGKVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYFQSGRSRTKRSWV
    WNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDEN
    TGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNE
    PKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP
    YFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTV
    TLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYK
    IVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADP
    RFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVA
    AHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNI
    TVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVI
    QKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGF
    RRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYV
    LPAGLST

Product Description

  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 200 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • CDH7
  • Full Name
  • Cadherin 7
  • Introduction
  • This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18.
  • Alternative Names
  • CDH7; CDH7L1; cadherin-7; cadherin 7, type 2; Cadherin 7

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