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Magic™ Membrane Protein Human CERS1 (Ceramide synthase 1) Full Length (CAT#: MPC4127K) Made to Order

This product is a made-to-order Human CERS1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CERS1
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 6
  • Sequence
  • MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLA
    EHAHLAPPELLLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMP
    ESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAA
    AYLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHN
    VGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFS
    WFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFL
    YIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAEKPLRNGLVKDKRF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • CERS1
  • Full Name
  • Ceramide synthase 1
  • Introduction
  • This gene encodes a ceramide synthase enzyme, which catalyzes the synthesis of ceramide, the hydrophobic moiety of sphingolipids. The encoded enzyme synthesizes 18-carbon (C18) ceramide in brain neurons. Elevated expression of this gene may be associated with increased longevity, while decreased expression of this gene may be associated with myoclonus epilepsy with dementia in human patients. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.
  • Alternative Names
  • CERS1; EPM8; GDF1; LAG1; UOG1; GDF-1; LASS1; Embryonic growth/differentiation factor 1; longevity assurance (LAG1, S. cerevisiae) homolog 1; longevity assurance gene 1 protein homolog 1; protein UOG-1; upstream of GDF1; Ceramide synthase 1

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