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Magic™ Membrane Protein Human CERS3 (Ceramide synthase 3) Full Length (CAT#: MPC4543K) Made to Order

Datasheet
This product is a made-to-order Human CERS3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CERS3
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 6
  • Sequence
  • MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLL
    IIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIY
    GLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGI
    AFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILEMSFYWSLLFRLGFDV
    KRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWLESAKM
    FSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFS
    YIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEE
    EEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • CERS3
  • Full Name
  • Ceramide synthase 3
  • Introduction
  • This gene is a member of the ceramide synthase family of genes. The ceramide synthase enzymes regulate sphingolipid synthesis by catalyzing the formation of ceramides from sphingoid base and acyl-coA substrates. This family member is involved in the synthesis of ceramides with ultra-long-chain acyl moieties (ULC-Cers), important to the epidermis in its role in creating a protective barrier from the environment. The protein encoded by this gene has also been implicated in modification of the lipid structures required for spermatogenesis. Mutations in this gene have been associated with male fertility defects, and epidermal defects, including ichthyosis. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • CERS3; ARCI9; LASS3; LAG1 homolog, ceramide synthase 3; LAG1 longevity assurance homolog 3; dihydroceramide synthase 3; sphingosine N-acyltransferase CERS3; Ceramide synthase 3

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