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Magic™ Membrane Protein Human CHST15 (Carbohydrate sulfotransferase 15) Expressed in NS0 for Antibody Discovery, Partial (99-561aa) (CAT#: MPX0448K)

Datasheet
This product is a 55 kDa Human CHST15 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CHST15
  • Protein Length
  • Partial (99-561aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 55 kDa
  • TMD
  • 1
  • Sequence
  • SG
    AHQELLISSPFHYGGFPSNPSLMDSENPSDTKEHHHQSSVNNISYMKDYP
    SIKLIINSITTRIEFTTRQLPDLEDLKKQELHMFSVIPNKFLPNSKSPCW
    YEEFSGQNTTDPYLTNSYVLYSKRFRSTFDALRKAFWGHLAHAHGKHFRL
    RCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRL
    RDGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASAS
    TMWDNNAWTFFYDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYS
    DYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPV
    RLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKVFQFLNLGP
    LSEKQEALMTKSPASNARRPEDRNLGPMWPITQKILRDFYRPFNARLAQV
    LADEAFAWKTT

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris and NaCl.

Target

  • Target Protein
  • CHST15
  • Full Name
  • Carbohydrate sulfotransferase 15
  • Introduction
  • Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
  • Alternative Names
  • CHST15; BRAG; GALNAC4S-6ST; B cell RAG associated protein (GALNAC4S-6ST); B-cell RAG-associated gene protein; carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; hBRAG; Carbohydrate sulfotransferase 15

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