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Magic™ Membrane Protein Human CLCA2 (Chloride channel accessory 2) Full Length (CAT#: MPC0477K) Made to Order

This product is a 103.9 kDa Human CLCA2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLCA2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 103.9 kDa
  • TMD
  • 1
  • Sequence
  • MTQRSIAGPICNLKFVTLLVALSSELPFLGAGVQLQDNGYNGLLIAINPQ
    VPENQNLISNIKEMITEASFYLFNATKRRVFFRNIKILIPATWKANNNSK
    IKQESYEKANVIVTDWYGAHGDDPYTLQYRGCGKEGKYIHFTPNFLLNDN
    LTAGYGSRGRVFVHEWAHLRWGVFDEYNNDKPFYINGQNQIKVTRCSSDI
    TGIFVCEKGPCPQENCIISKLFKEGCTFIYNSTQNATASIMFMQSLSSVV
    EFCNASTHNQEAPNLQNQMCSLRSAWDVITDSADFHHSFPMNGTELPPPP
    TFSLVQAGDKVVCLVLDVSSKMAEADRLLQLQQAAEFYLMQIVEIHTFVG
    IASFDSKGEIRAQLHQINSNDDRKLLVSYLPTTVSAKTDISICSGLKKGF
    EVVEKLNGKAYGSVMILVTSGDDKLLGNCLPTVLSSGSTIHSIALGSSAA
    PNLEELSRLTGGLKFFVPDISNSNSMIDAFSRISSGTGDIFQQHIQLEST
    GENVKPHHQLKNTVTVDNTVGNDTMFLVTWQASGPPEIILFDPDGRKYYT
    NNFITNLTFRTASLWIPGTAKPGHWTYTLNNTHHSLQALKVTVTSRASNS
    AVPPATVEAFVERDSLHFPHPVMIYANVKQGFYPILNATVTATVEPETGD
    PVTLRLLDDGAGADVIKNDGIYSRYFFSFAANGRYSLKVHVNHSPSISTP
    AHSIPGSHAMYVPGYTANGNIQMNAPRKSVGRNEEERKWGFSRVSSGGSF
    SVLGVPAGPHPDVFPPCKIIDLEAVKVEEELTLSWTAPGEDFDQGQATSY
    EIRMSKSLQNIQDDFNNAILVNTSKRNPQQAGIREIFTFSPQISTNGPEH
    QPNGETHESHRIYVAIRAMDRNSLQSAVSNIAQAPLFIPPNSDPVPARDY
    LILKGVLTAMGLIGIICLIIVVTHHTLSRKKRADKKENGTKLL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CLCA2
  • Full Name
  • Chloride channel accessory 2
  • Introduction
  • This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. The encoded protein is autoproteolytically processed to generate N- and C- terminal fragments. Expression of this gene is upregulated by the tumor suppressor protein p53 in response to DNA damage. In breast cancer, expression of this gene is downregulated and the encoded protein may inhibit migration and invasion while promoting mesenchymal-to-epithelial transition in cancer cell lines.
  • Alternative Names
  • CACC; CACC3; CLCRG2; CaCC-3; calcium-activated chloride channel regulator 2; CLCA family member 2, chloride channel regulator; calcium-activated chloride channel protein 3; chloride channel, calcium activated, family member 2; CLCA2; Chloride channel accessory 2

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