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Magic™ Membrane Protein Human CNNM2 (Cyclin and CBS domain divalent metal cation transport mediator 2) Full Length (CAT#: MPC0495K) Made to Order

This product is a 96.6 kDa Human CNNM2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CNNM2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 96.6 kDa
  • TMD
  • 4
  • Sequence
  • MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLP
    LLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEGGALRVSERTR
    VKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRC
    GIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPAL
    GAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKK
    FLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKN
    YAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTI
    GIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCV
    LGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVM
    TPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDL
    AFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQR
    VNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHR
    ERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILL
    RLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGK
    EGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTELLAAGSPGENKSP
    PRPCGLNHSDSLSRSDRIDAVTPTLGSSNNQLNSSLLQVYIPDYSVRALS
    DLQFVKISRQQYQNALMASRMDKTPQSSDSENTKIELTLTELHDGLPDET
    ANLLNEQNCVTHSKANHSLHNEGAI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CNNM2
  • Full Name
  • Cyclin and CBS domain divalent metal cation transport mediator 2
  • Introduction
  • This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Alternative Names
  • ACDP2; HOMG6; HOMGSMR; metal transporter CNNM2; ancient conserved domain-containing protein 2; cyclin M2; CNNM2; Cyclin and CBS domain divalent metal cation transport mediator 2

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