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Magic™ Membrane Protein Human CYP39A1 (Cytochrome P450 family 39 subfamily A member 1) Full Length (CAT#: MPC4729K) Made to Order

This product is a made-to-order Human CYP39A1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CYP39A1
  • Protein Length
  • Full length
  • Protein Class
  • Oxidoreductase
  • TMD
  • 3
  • Sequence
  • MELISPTVIIILGCLALFLLLQRKNLRRPPCIKGWIPWIGVGFEFGKAPL
    EFIEKARIKYGPIFTVFAMGNRMTFVTEEEGINVFLKSKKVDFELAVQNI
    VYRTASIPKNVFLALHEKLYIMLKGKMGTVNLHQFTGQLTEELHEQLENL
    GTHGTMDLNNLVRHLLYPVTVNMLFNKSLFSTNKKKIKEFHQYFQVYDED
    FEYGSQLPECLLRNWSKSKKWFLELFEKNIPDIKACKSAKDNSMTLLQAT
    LDIVETETSKENSPNYGLLLLWASLSNAVPVAFWTLAYVLSHPDIHKAIM
    EGISSVFGKAGKDKIKVSEDDLENLLLIKWCVLETIRLKAPGVITRKVVK
    PVEILNYIIPSGDLLMLSPFWLHRNPKYFPEPELFKPERWKKANLEKHSF
    LDCFMAFGSGKFQCPARWFALLEVQMCIILILYKYDCSLLDPLPKQSYLH
    LVGVPQPEGQCRIEYKQRI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • CYP39A1
  • Full Name
  • Cytochrome P450 family 39 subfamily A member 1
  • Introduction
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • CYP39A1; 24-hydroxycholesterol 7-alpha-hydroxylase; cytochrome P450, family 39, subfamily A, polypeptide 1; cytochrome P450, subfamily XXXIX (oxysterol 7 alpha-hydroxylase), polypeptide 1; Cytochrome P450 family 39 subfamily A member 1

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