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Magic™ Membrane Protein Human DSG2 (Desmoglein 2) Full Length (CAT#: MPC2597K) Made to Order

This product is a made-to-order Human DSG2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DSG2
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • TMD
  • 1
  • Sequence
  • MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRA
    WITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFG
    IFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVL
    DINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRI
    VSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTD
    KPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADE
    IGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDF
    SVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSES
    MDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLA
    KLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLI
    EPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQE
    STSVLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCR
    EAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAKGFTPIPGT
    IEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSS
    SASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTKTARA
    TGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYS
    QEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCLGQKIDINKE
    IEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAE
    KVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPTT
    VILGPSQPQSLIVTERVYAPASTLVDQPYANEGTVVVTERVIQPHGGGSN
    PLEGTQHLQDVPYVMVRERESFLAPSSGVQPTLAMPNIAVGQNVTVTERV
    LAPASTLQSSYQIPTENSMTARNTTVSGAGVPGPLPDFGLEESGHSNSTI
    TTSSTRVTKHSTVQHSYS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • DSG2
  • Full Name
  • Desmoglein 2
  • Introduction
  • This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
  • Alternative Names
  • DSG2; HDGC; CDHF5; desmoglein-2; cadherin family member 5; Desmoglein 2

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