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Magic™ Membrane Protein Human ERAP1 (Endoplasmic reticulum aminopeptidase 1) Full Length (CAT#: MPC3508K) Made to Order

This product is a made-to-order Human ERAP1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ERAP1
  • Protein Length
  • Full length
  • Protein Class
  • Immunity
  • TMD
  • 1
  • Sequence
  • MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWN
    KIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHL
    QISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIH
    YAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFK
    ASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFI
    ISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP
    YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMT
    VAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYF
    FGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLRE
    YLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSR
    SQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMKQEHYM
    KGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF
    NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIG
    KLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFK
    AFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGY
    FRKWKESNGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQ
    IEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAW
    QFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE
    NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • ERAP1
  • Full Name
  • Endoplasmic reticulum aminopeptidase 1
  • Introduction
  • The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.
  • Alternative Names
  • ERAP1; ALAP; A-LAP; ARTS1; ERAAP; APPILS; ARTS-1; ERAAP1; PILSAP; PILS-AP; CTD-2260A17.2; adipocyte-derived leucine aminopeptidase; aminopeptidase PILS; aminopeptidase regulator of TNFR1 shedding; endoplasmic reticulum aminopeptidase associated with antigen processing; puromycin-insensitive leucyl-specific aminopeptidase; type 1 tumor necrosis factor receptor shedding aminopeptidase regulator; Endoplasmic reticulum aminopeptidase 1

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