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Magic™ Membrane Protein Human ERMARD (ER membrane associated RNA degradation) Full Length (CAT#: MPC2676K) Made to Order

This product is a made-to-order Human ERMARD membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ERMARD
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • TMD
  • 2
  • Sequence
  • MEVLIGDPITTCLSPSVYDIICNLGFQLRENCDINSIVTQNGEVCWKTIT
    DCVSYTESEQGLDYWGSVRLLGPVCEAVHSHFLSLTKGQFEIRYAPWFQW
    TSFPELFPEIFDALESLQSPAISLSLMKLTSCLERALGDVFLLIGKECPF
    LLRDLLSSEELAQVFSQSVMNVLKVFVGSPCGLNLRNVLWHGFASPEEIP
    PKYCSMMILLTAGLGQLLKSYLQNTKLTLAHRSFISLTNLEDLIVFPDVT
    YEVLSVLEEVMMKSAFILKIMLPYWEVALVKFKSHRFADCAILLLTQLET
    GLRNVFATLNRCPKRLLTAESTALYTTFDQILAKHLNDGKINQLPLFLGE
    PAMEFLWDFLNHQEGPRIRDHLSHGEINLHEFSKETTNQLLAFSLVLLLR
    FVDDCLLSVFKEKSAVELLISLAEGYSSRCHPVFQLKKQVLSCEESIRVW
    ALLPFPEELTRQAVRLEDNSETNACHSLITKMTDELYHHMPENRCVLKDL
    DRLPTETWPQLLRELCSTPVPTLFCPRIVLEVLVVLRSISEQCRRVSSQV
    TVASELRHRQWVERTLRSRQRQNYLRMWSSIRLLSPVLSLILLLIALELV
    NIHAVCGKNAHEYQQYLKFVKSILQYTENLVAYTSYEKNKWNETINLTHT
    ALLKMWTFSEKKQMLIHLAKKSTSKVLL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • ERMARD
  • Full Name
  • ER membrane associated RNA degradation
  • Introduction
  • The protein encoded by this gene contains 2 transmembrane domains near the C-terminus and is localized in the endoplasmic reticulum. Knockout of this gene in developing rat brain showed that it may be involved in neuronal migration. Mutations in this gene are associated with periventricular nodular heterotopia-6 (PVNH6). Alternatively spliced transcript variants have been found for this gene.
  • Alternative Names
  • ERMARD; PVNH6; C6orf70; dJ266L20.3; endoplasmic reticulum membrane-associated RNA degradation protein; transmembrane protein C6orf70; ER membrane associated RNA degradation

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