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Magic™ Membrane Protein Human EXT1 (Exostosin glycosyltransferase 1) Expressed in CHO for Antibody Discovery, Partial (69-746aa) (CAT#: MPX0294K)

This product is a 79 kDa Human EXT1 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • EXT1
  • Protein Length
  • Partial (69-746aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 79 kDa
  • TMD
  • 1
  • Sequence
  • DQLENEDSSVHISPRQKRDANSSIYKGKKCRM
    ESCFDFTLCKKNGFKVYVYPQQKGEKIAESYQNILAAIEGSRFYTSDPSQ
    ACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWNNGRNHLIFNLYSGTW
    PDYTEDVGFDIGQAMLAKASISTENFRPNFDVSIPLFSKDHPRTGGERGF
    LKFNTIPPLRKYMLVFKGKRYLTGIGSDTRNALYHVHNGEDVVLLTTCKH
    GKDWQKHKDSRCDRDNTEYEKYDYREMLHNATFCLVPRGRRLGSFRFLEA
    LQAACVPVMLSNGWELPFSEVINWNQAAVIGDERLLLQIPSTIRSIHQDK
    ILALRQQTQFLWEAYFSSVEKIVLTTLEIIQDRIFKHISRNSLIWNKHPG
    GLFVLPQYSSYLGDFPYYYANLGLKPPSKFTAVIHAVTPLVSQSQPVLKL
    LVAAAKSQYCAQIIVLWNCDKPLPAKHRWPATAVPVVVIEGESKVMSSRF
    LPYDNIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWD
    NSKERWGYTSKWTNDYSMVLTGAAIYHKYYHYLYSHYLPASLKNMVDQLA
    NCEDILMNFLVSAVTKLPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQ
    RQSCMNTFASWFGYMPLIHSQMRLDPVLFKDQVSILRKKYRDIERL

Product Description

  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris, NaCl and Glycerol.

Target

  • Target Protein
  • EXT1
  • Full Name
  • Exostosin glycosyltransferase 1
  • Introduction
  • This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.
  • Alternative Names
  • EXT1; EXT; LGS; TTV; LGCR; TRPS2; exostosin-1; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase; Langer-Giedion syndrome chromosome region; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; exostoses (multiple) 1; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; multiple exostoses protein 1; putative tumor suppressor protein EXT1; Exostosin glycosyltransferase 1

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