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Magic™ Membrane Protein Human FA2H (Fatty acid 2-hydroxylase) Full Length (CAT#: MPC4436K) Made to Order

This product is a made-to-order Human FA2H membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FA2H
  • Protein Length
  • Full length
  • Protein Class
  • Oxidoreductase
  • TMD
  • 4
  • Sequence
  • MAPAPPPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLL
    RARAGQDISADLDGPPHRHSANARRWLEQYYVGELRGEQQGSMENEPVAL
    EETQKTDPAMEPRFKVVDWDKDLVDWRKPLLWQVGHLGEKYDEWVHQPVT
    RPIRLFHSDLIEGLSKTVWYSVPIIWVPLVLYLSWSYYRTFAQGNVRLFT
    SFTTEYTVAVPKSMFPGLFMLGTFLWSLIEYLIHRFLFHMKPPSDSYYLI
    MLHFVMHGQHHKAPFDGSRLVFPPVPASLVIGVFYLCMQLILPEAVGGTV
    FAGGLLGYVLYDMTHYYLHFGSPHKGSYLYSLKAHHVKHHFAHQKSGFGI
    STKLWDYCFHTLTPEKPHLKTQ

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • FA2H
  • Full Name
  • Fatty acid 2-hydroxylase
  • Introduction
  • This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.
  • Alternative Names
  • FA2H; FAAH; FAH1; SCS7; SPG35; FAXDC1; fatty acid alpha-hydroxylase; fatty acid hydroxylase domain containing 1; fatty acid hydroxylase domain-containing protein 1; spastic paraplegia 35 (autosomal recessive); Fatty acid 2-hydroxylase

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