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Magic™ Membrane Protein Human FCRL3 (Fc receptor like 3) Expressed in NS0 for Antibody Discovery, Partial (14-569aa) (CAT#: MPX0556K)

Datasheet
This product is a 62.2 kDa Human FCRL3 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FCRL3
  • Protein Length
  • Partial (14-569aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 62.2 kDa
  • TMD
  • 1
  • Sequence
  • REQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYH
    DEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNVILRC
    QGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKP
    LNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWS
    RSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLI
    EGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAA
    DNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHE
    DVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTL
    RAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSG
    NYSCEADNGLGAQHSKVVTLNVTGTSRNR

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • FCRL3
  • Full Name
  • Fc receptor like 3
  • Introduction
  • This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • FCRL3; FCRH3; IFGP3; IRTA3; SPAP2; CD307c; Fc receptor-like protein 3; Fc receptor homolog 3; IFGP family protein 3; SH2 domain-containing phosphatase anchor protein 2; fcR-like protein 3; hIFGP3; immune receptor translocation-associated protein 3; immunoglobulin superfamily receptor translocation associated protein 3; Fc receptor like 3

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