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Magic™ Membrane Protein Human FLRT2 (Fibronectin leucine rich transmembrane protein 2) Expressed in NS0 for Antibody Discovery, Partial (36-539aa) (CAT#: MPX0114K)

Datasheet
This product is a 57.1 kDa Human FLRT2 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FLRT2
  • Protein Length
  • Partial (36-539aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 57.1 kDa
  • TMD
  • 1
  • Sequence
  • CPSVCRCDRNFVYCN
    ERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQL
    DEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGV
    EDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAF
    QNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLP
    GTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLS
    NLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAV
    RELNMNLLSCPTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTP
    TTSKLPTIPDWDGRERVTPPISERIQLSIHFVNDTSIQVSWLSLFTVMAY
    KLTWVKMGHSLVGGIVQERIVSGEKQHLSLVNLEPRSTYRICLVPLDAFN
    YRAVEDTICSEATTHASYLNNGSNTASSHEQTTSHSMGS

Product Description

  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 200 μg/mL in sterile PBS.
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • FLRT2
  • Full Name
  • Fibronectin leucine rich transmembrane protein 2
  • Introduction
  • This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • FLRT2; Leucine-rich repeat transmembrane protein FLRT2; fibronectin-like domain-containing leucine-rich transmembrane protein 2; KIAA0405; UNQ232/PRO265; Fibronectin leucine rich transmembrane protein 2

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