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Magic™ Membrane Protein Human GABRA1 (Gamma-aminobutyric acid type A receptor subunit alpha1) Full Length (CAT#: MPC0509K) Made to Order

This product is a 51.8 kDa Human GABRA1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GABRA1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 51.8 kDa
  • TMD
  • 4
  • Sequence
  • MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLL
    DGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDE
    RLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITE
    DGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTR
    EPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKI
    GYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
    RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV
    PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEV
    KPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLK
    APTPHQ

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • FLAG tag at N-terminus and Rhodopsin-1D4 tag at C-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GABRA1
  • Full Name
  • Gamma-aminobutyric acid type A receptor subunit alpha1
  • Introduction
  • This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
  • Alternative Names
  • EJM; ECA4; EJM5; DEE19; EIEE19; GABA(A) receptor subunit alpha-1; GABA(A) receptor, alpha 1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; gamma-aminobutyric acid type A receptor alpha1 subunit; GABRA1; Gamma-aminobutyric acid type A receptor subunit alpha1

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