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Magic™ Membrane Protein Human GABRD (Gamma-aminobutyric acid type A receptor subunit delta) Full Length (CAT#: MPC0518K) Made to Order

This product is a 50.7 kDa Human GABRD membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GABRD
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 50.7 kDa
  • TMD
  • 4
  • Sequence
  • MDAPARLLAPLLLLCAQQLRGTRAMNDIGDYVGSNLEISWLPNLDGLIAG
    YARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRL
    SYNHTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDG
    VILYSIRITSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQ
    EHIHGLDKLQLAQFTITSYRFTTELMNFKSAGQFPRLSLHFHLRRNRGVY
    IIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSS
    LPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSRP
    RAEMDVRNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGE
    TKKEGAARSGGQGGIRARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY
    AM

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GABRD
  • Full Name
  • Gamma-aminobutyric acid type A receptor subunit delta
  • Introduction
  • Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
  • Alternative Names
  • EJM7; EIG10; GEFSP5; gamma-aminobutyric acid receptor subunit delta; GABA(A) receptor subunit delta; GABA(A) receptor, delta; GABA-A receptor, delta polypeptide; gamma-aminobutyric acid (GABA) A receptor, delta; gamma-aminobutyric acid type A receptor delta subunit; GABRD; Gamma-aminobutyric acid type A receptor subunit delta

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