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Magic™ Membrane Protein Human GABRG3 (Gamma-aminobutyric acid type A receptor subunit gamma3) Full Length (CAT#: MPC0522K) Made to Order

This product is a 54.2 kDa Human GABRG3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GABRG3
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 54.2 kDa
  • TMD
  • 4
  • Sequence
  • MAPKLLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLI
    LNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQ
    TWTDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQL
    LRIWNDGKILYTLRLTINAECQLQLHNFPMDEHSCPLIFSSYGYPKEEMI
    YRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIYFELS
    RRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLS
    TIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTK
    KTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEF
    EDTCVYECLDGKDCQSFFCCYEECKSGSWRKGRIHIDILELDSYSRVFFP
    TSFLLFNLVYWVGYLYL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GABRG3
  • Full Name
  • Gamma-aminobutyric acid type A receptor subunit gamma3
  • Introduction
  • This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene.
  • Alternative Names
  • Gamma-aminobutyric acid receptor subunit gamma-3; GABA(A) receptor subunit gamma-3; GABA(G) receptor, gamma 3; gamma-aminobutyric acid (GABA) A receptor, gamma 3; gamma-aminobutyric acid type A receptor gamma3 subunit; GABRG3; Gamma-aminobutyric acid type A receptor subunit gamma3

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