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Magic™ Membrane Protein Human GIPR (Gastric inhibitory polypeptide receptor) Full Length (CAT#: MPC0328K) Made to Order

This product is a 53.1 kDa Human GIPR membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GIPR
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 53.1 kDa
  • TMD
  • 7
  • Sequence
  • MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETL
    AAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVL
    RQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLA
    TLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPY
    LGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGG
    SEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
    TPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLL
    GVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQ
    SEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGT
    LPGPGNEASRELESYC

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GIPR
  • Full Name
  • Gastric inhibitory polypeptide receptor
  • Introduction
  • This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
  • Alternative Names
  • PGQTL2; gastric inhibitory polypeptide receptor; GIP-R; glucose-dependent insulinotropic polypeptide receptor; GIPR; Gastric inhibitory polypeptide receptor

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