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Magic™ Membrane Protein Human GJA8 (Gap junction protein alpha 8) Full Length (CAT#: MPC0532K) Made to Order

This product is a 48.2 kDa Human GJA8 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GJA8
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 48.2 kDa
  • TMD
  • 4
  • Sequence
  • MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQS
    DFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV
    RMEEKRKSREAEELGQQAGTNGGPDQGSVKKSSGSKGTKKFRLEGTLLRT
    YICHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPT
    EKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPVEQPLGEIPEK
    SLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
    EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKK
    EEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEK
    TPSLCPELTTDDARPLSRLSKASSRARSDDLTV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GJA8
  • Full Name
  • Gap junction protein alpha 8
  • Introduction
  • This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
  • Alternative Names
  • CAE; CAE1; CX50; CZP1; MP70; CTRCT1; gap junction alpha-8 protein; cell surface glycoprotein; connexin 50; gap junction alpha 8; gap junction membrane channel protein alpha-8; gap junction protein alpha 8 50kDa; lens fiber protein MP70; lens intrinsic membrane protein MP70; GJA8; Gap junction protein alpha 8

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