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Magic™ Membrane Protein Human GLRB (Glycine receptor beta) Full Length (CAT#: MPC0552K) Made to Order

This product is a 56.1 kDa Human GLRB membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GLRB
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 56.1 kDa
  • TMD
  • 4
  • Sequence
  • MKFLLTTAFLILISLWVEEAYSKEKSSKKGKGKKKQYLCPSQQSAEDLAR
    VPANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMD
    YRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKS
    ANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQ
    LESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKEDIEYGNCTKYYKGT
    GYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVP
    LGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVV
    QVMLNNPKRVEAEKARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQV
    GETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGK
    SQAKNNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GLRB
  • Full Name
  • Glycine receptor beta
  • Introduction
  • This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • HKPX2; glycine receptor subunit beta; glycine receptor 58 kDa subunit; glycine receptor, beta subunit; GLRB; Glycine receptor beta

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