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Magic™ Membrane Protein Human GNAI3 (G protein subunit alpha i3) for Antibody Discovery (CAT#: MP1355J)

Datasheet
This product is a 44.5 kDa Human GNAI3 membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GNAI3
  • Protein Length
  • Full-length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 44.5 kDa
  • TMD
  • 7
  • Sequence
  • MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY

Product Description

  • Expression Systems
  • E.coli
  • Tag
  • N-6xHis
  • Reconstitution
  • Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration).
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Liquid: Tris/PBS-based buffer, 5%-50% glycerol
    Lyophilized powder: Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Target

  • Target Protein
  • GNAI3
  • Full Name
  • G protein subunit alpha i3
  • Introduction
  • Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.
  • Alternative Names
  • 87U6; FLJ26559; G protein alpha inhibiting 3; G(i) alpha 3; G(i) alpha-3; GNAI3; GNAI3_HUMAN; Guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 3; Guanine nucleotide binding protein G(k) alpha subunit; Guanine nucleotide-binding protein G(k) subunit alpha; OTTHUMP00000013368

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