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Magic™ Membrane Protein Human GPR150 (G protein-coupled receptor 150) Full Length (CAT#: MPC0128K) Made to Order

This product is a 46.3 kDa Human GPR150 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR150
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 46.3 kDa
  • TMD
  • 7
  • Sequence
  • MEDLFSPSILPPAPNISVPILLGWGLNLTLGQGAPASGPPSRRVRLVFLG
    VILVVAVAGNTTVLCRLCGGGGPWAGPKRRKMDFLLVQLALADLYACGGT
    ALSQLAWELLGEPRAATGDLACRFLQLLQASGRGASAHLVVLIALERRRA
    VRLPHGRPLPARALAALGWLLALLLALPPAFVVRGDSPSPLPPPPPPTSL
    QPGAPPAARAWPGERRCHGIFAPLPRWHLQVYAFYEAVAGFVAPVTVLGV
    ACGHLLSVWWRHRPQAPAAAAPWSASPGRAPAPSALPRAKVQSLKMSLLL
    ALLFVGCELPYFAARLAAAWSSGPAGDWEGEGLSAALRVVAMANSALNPF
    VYLFFQAGDCRLRRQLRKRLGSLCCAPQGGAEDEEGPRGHQALYRQRWPH
    PHYHHARREPLDEGGLRPPPPRPRPLPCSCESAF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • GPR150
  • Full Name
  • G protein-coupled receptor 150
  • Introduction
  • This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes.
  • Alternative Names
  • PGR11; probable G-protein coupled receptor 150; seven transmembrane helix receptor; GPR150; G protein-coupled receptor 150

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