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Magic™ Membrane Protein Human HCN2 (Hyperpolarization activated cyclic nucleotide gated potassium channel 2) Full Length (CAT#: MPC0574K) Made to Order

This product is a 96.9 kDa Human HCN2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HCN2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 96.9 kDa
  • TMD
  • 6
  • Sequence
  • MDARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPA
    PPQHPPRAEALPPEAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNG
    ECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEAG
    PAGEPRGSQASFMQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAG
    AWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVV
    SDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIP
    VDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW
    EEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWV
    SINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIV
    GATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKI
    HDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADP
    NFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMK
    LSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR
    AFETVAIDRLDRIGKKNSILLHKVQHDLNSGVFNNQENAIIQEIVKYDRE
    MVQQAELGQRVGLFPPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPL
    ALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPA
    APLAGPALPARRLSRASRPLSASQPSLPHGAPGPAASTRPASSSTPRLGP
    TPAARAAAPSPDRRDSASPGAAGGLDPQDSARSRLSSNL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • HCN2
  • Full Name
  • Hyperpolarization activated cyclic nucleotide gated potassium channel 2
  • Introduction
  • The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy.
  • Alternative Names
  • BCNG2; HAC-1; BCNG-2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2; brain cyclic nucleotide-gated channel 2; hyperpolarization activated cyclic nucleotide gated potassium channel 2; HCN2; Hyperpolarization activated cyclic nucleotide gated potassium channel 2

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