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Magic™ Membrane Protein Human HPN (Hepsin) Full Length (CAT#: MPC0999K) Made to Order

This product is a 45 kDa Human HPN membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HPN
  • Protein Length
  • Full length
  • Protein Class
  • Protease
  • Molecular Weight
  • 45 kDa
  • TMD
  • 1
  • Sequence
  • MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEP
    LYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALT
    HSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAIC
    QDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLT
    AAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPN
    SEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ
    YYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQ
    GDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI
    FQAIKTHSEASGMVTQL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • HPN
  • Full Name
  • Hepsin
  • Introduction
  • This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • HPN; TMPRSS1; serine protease hepsin; testicular tissue protein Li 85; transmembrane protease serine 1; Hepsin

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