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Magic™ Membrane Protein Human HTR1B (5-hydroxytryptamine receptor 1B) Full Length (CAT#: MPC0202K) Made to Order

This product is a 43.5 kDa Human HTR1B membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HTR1B
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 43.5 kDa
  • TMD
  • 7
  • Sequence
  • MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKV
    LLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSI
    LVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWA
    ITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECV
    VNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKR
    LTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
    KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAI
    FDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag tag and 10× His tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • HTR1B
  • Full Name
  • 5-hydroxytryptamine receptor 1B
  • Introduction
  • The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs.
  • Alternative Names
  • S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT-1B; 5-HT1DB; 5-HT-1D-beta; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; serotonin 1D beta receptor; serotonin receptor 1B; HTR1B; 5-hydroxytryptamine receptor 1B

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