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Magic™ Membrane Protein Human ICAM2 (Intercellular adhesion molecule 2) Expressed in NS0 for Antibody Discovery, Partial (25-223aa) (CAT#: MPX0501K)

Datasheet
This product is a 50 kDa Human ICAM2 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ICAM2
  • Protein Length
  • Partial (25-223aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 50 kDa
  • TMD
  • 1
  • Sequence
  • KVFEVHVRPKKLAVEPKGSLEVNCST
    TCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQE
    SMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLF
    RGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRG
    GNIFHKHSAPKMLEIYEPVSDSQ

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc and 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 0.4 mg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS containing Calcium and Magnesium with Sorbitol.

Target

  • Target Protein
  • ICAM2
  • Full Name
  • Intercellular adhesion molecule 2
  • Introduction
  • The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
  • Alternative Names
  • ICAM2; CD102; ICAM-2; Intercellular adhesion molecule 2

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