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Magic™ Membrane Protein Human IL11RA (Interleukin 11 receptor subunit alpha) Expressed in CHO for Antibody Discovery, Partial (24-363aa) (CAT#: MPX0558K)

This product is a 38 kDa Human IL11RA membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL11RA
  • Protein Length
  • Partial (24-363aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 38 kDa
  • TMD
  • 1
  • Sequence
  • SPCPQAWGPPGVQYGQPGRSVKLCCPG
    VTAGDPVSWFRDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGA
    LGGTVTLQLGYPPARPVVSCQAADYENFSCTWSPSQISGLPTRYLTSYRK
    KTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNP
    LGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPCQP
    HFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLD
    AGTWSTWSPEAWGTPSTGTIPKEIPAWGQLHTQPEVEPQVDSPAPPRPSL
    QPHPRLLDHRDSV

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • IL11RA
  • Full Name
  • Interleukin 11 receptor subunit alpha
  • Introduction
  • Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.
  • Alternative Names
  • IL11RA; CRSDA; interleukin-11 receptor subunit alpha; IL-11 receptor subunit alpha; IL-11R subunit alpha; interleukin 11 receptor, alpha; interleukin-11 receptor alpha chain; Interleukin 11 receptor subunit alpha

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