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Magic™ Membrane Protein Human IL23R (Interleukin 23 receptor) Expressed in NS0 for Antibody Discovery, Partial (24-353aa) (CAT#: MPX0650K)

This product is a 64 kDa Human IL23R membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL23R
  • Protein Length
  • Partial (24-353aa)
  • Protein Class
  • Receptor; Immunity
  • Molecular Weight
  • 64 kDa
  • TMD
  • 1
  • Sequence
  • GITNINCSGHIWVEPATIFKMGMNISI
    YCQAAIKNCQPRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMY
    CTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGK
    LTYIDTKYVVHVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAAN
    ALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTIIYWDSQTTIEK
    VSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG
    KRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDN
    RGD

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • IL23R
  • Full Name
  • Interleukin 23 receptor
  • Introduction
  • The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
  • Alternative Names
  • IL23R; interleukin-23 receptor; IL-23 receptor; Interleukin 23 receptor

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