Magic™ Membrane Protein Human IL27RA (Interleukin 27 receptor subunit alpha) Expressed in NS0 for Antibody Discovery, Partial (34-516aa) (CAT#: MPX0302K)

Datasheet

This product is a 79 kDa Human IL27RA membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

Host Species
Human

Target Protein
IL27RA

Protein Length
Partial (34-516aa)

Protein Class
Receptor

Molecular Weight
79 kDa

Sequence
GSAGPLQCYGVGPLGDL
NCSWEPLGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMS
DKLLVWGTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEATVH
WAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELAT
GYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSGNLCGTPGGEE
PLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWARVSA
VNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLE
HVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASG
LASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLT
HYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCELWVTASTIAGQGPP
GPILRLHLPDNTLRWK

Product Description

Expression Systems
NS0

Tag
hIgG1 Fc tag at the C-terminus

Protein Format
Soluble

Reconstitution
Reconstitute at 100 μg/mL in sterile PBS.

Endotoxin
<0.10 EU per 1 μg of the protein by the LAL method.

Purity
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

Buffer
Lyophilized from a 0.2 μm filtered solution in PBS.

Target

Target Protein
IL27RA

Full Name
Interleukin 27 receptor subunit alpha

Introduction
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.

Alternative Names
IL27RA; CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1; interleukin-27 receptor subunit alpha; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; T-cell cytokine receptor type 1; class I; cytokine receptor; cytokine receptor WSX-1; cytokine receptor-like 1; interleukin 27 receptor, alpha; type I T-cell cytokine receptor; Interleukin 27 receptor subunit alpha

Gene ID
9466

UniProt ID
Q6UWB1

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