Magic™ Membrane Protein Human IL31RA (Interleukin 31 receptor A) Expressed in NS0 for Antibody Discovery, Partial (20-516aa) (CAT#: MPX0478K)

Datasheet

This product is a 57.5 kDa Human IL31RA membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

Host Species
Human

Target Protein
IL31RA

Protein Length
Partial (20-516aa)

Protein Class
Receptor; Immunity

Molecular Weight
57.5 kDa

Sequence
ALPAKPENISCVYYYRKNLTCTWSPGKETSY
TQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEA
ENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVLGIKRMIQIEWIKPELA
PVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTGLQPFTEYVIA
LRCAVKESKFWSDWSQEKMGMTEEEAPCGLELWRVLKPAEADGRRPVRLL
WKKARGAPVLEKTLGYNIWYYPESNTNLTETMNTTNQQLELHLGGESFWV
SMISYNSLGKSPVATLRIPAIQEKSFQCIEVMQACVAEDQLVVKWQSSAL
DVNTWMIEWFPDVDSEPTTLSWESVSQATNWTIQQDKLKPFWCYNISVYP
MLHDKVGEPYSIQAYAKEGVPSEGPETKVENIGVKTVTITWKEIPKSERK
GIICNYTIFYQAEGGKGFSKTVNSSILQYGLESLKRKTSYIVQVMASTSA
GGTNGTSINFKTLSFS

Product Description

Activity
Yes

Expression Systems
NS0

Tag
6xHis tag at the C-terminus

Protein Format
Soluble

Reconstitution
Reconstitute at 100 μg/mL in sterile PBS.

Endotoxin
<0.10 EU per 1 μg of the protein by the LAL method.

Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

Buffer
Lyophilized from a 0.2 μm filtered solution in PBS.

Target

Target Protein
IL31RA

Full Name
Interleukin 31 receptor A

Introduction
The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Alternative Names
IL31RA; CRL; GPL; CRL3; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384; zcytoR17; interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; class I cytokine receptor; cytokine receptor-like 3; gp130-like monocyte receptor; soluble type I cytokine receptor CRL3; Interleukin 31 receptor A

Gene ID
133396

UniProt ID
Q8NI17

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