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Magic™ Membrane Protein Human IL7R (Interleukin 7 receptor) Expressed in NS0 for Antibody Discovery, Partial (21-261aa) (CAT#: MPX0600K)

Datasheet
This product is a 54.5 kDa Human IL7R membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL7R
  • Protein Length
  • Partial (21-261aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 54.5 kDa
  • TMD
  • 1
  • Sequence
  • ESGYAQNGDLEDAELDDYSFSCYSQLEVNGSQHSLTCAFE
    DPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKK
    IDLTTIVKPEAPFDLSVIYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTH
    VNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSSGLSLS
    YGPVSPIIRRLWNIFVRNQEK

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • IL7R
  • Full Name
  • Interleukin 7 receptor
  • Introduction
  • The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
  • Alternative Names
  • IL7R; ILRA; CD127; IL7RA; CDW127; IL-7R-alpha; interleukin-7 receptor subunit alpha; CD127 antigen; IL-7 receptor subunit alpha; IL-7R subunit alpha; interleukin 7 receptor alpha chain; Interleukin 7 receptor

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