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Magic™ Membrane Protein Human ITGAV (Integrin subunit alpha V) Expressed in Yeast with 6xHis tag at the N-terminus for Antibody Discovery, Partial (891-1048aa) (CAT#: MPX4400K)

Datasheet
This product is a 19.7kDa Human ITGAV membrane protein expressed in Yeast. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ITGAV
  • Protein Length
  • Partial (891-1048aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 19.7kDa
  • TMD
  • 1
  • Sequence
  • DLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET

Product Description

  • Expression Systems
  • Yeast
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Purity
  • >90% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • ITGAV
  • Full Name
  • Integrin subunit alpha V
  • Introduction
  • The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
  • Alternative Names
  • ITGAV; CD51; MSK8; VNRA; VTNR; integrin alpha-V; antigen identified by monoclonal antibody L230; integrin alphaVbeta3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); vitronectin receptor subunit alpha; CD_antigen: CD51; Integrin subunit alpha V

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