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Magic™ Membrane Protein Human ITPR1 (Inositol 1,4,5-trisphosphate receptor type 1) Full Length (CAT#: MPC1042K) Made to Order

This product is a 313.9 kDa Human ITPR1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ITPR1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 313.9 kDa
  • TMD
  • 6
  • Sequence
  • MSDKMSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPP
    KKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEK
    KQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVT
    LDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQL
    VDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKF
    LTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWN
    SLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEK
    MVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVH
    STNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDAS
    KVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFS
    KPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFR
    HICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLH
    NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQE
    LICKAVLNPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLF
    WRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQY
    LAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVT
    PVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVC
    QRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVH
    VTTIFPISKMAKGEENKGNNDVEKLKSSNVMRSIHGVGELMTQVVLRGGG
    FLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRI
    SCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGI
    FGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQR
    QEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPD
    ETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQE
    SASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEF
    LQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINER
    VVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGED
    VLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNV
    YTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEI
    YTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFF
    SSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLS
    DVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDSVL
    AASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENT
    DARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGE
    KLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLVN
    RYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSL
    AEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHS
    FFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVD
    RDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQP
    GEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN
    NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTE
    YCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNA
    SKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENG
    EDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKH
    TAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKIND
    FFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVA
    FFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTIL
    RLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEF
    LYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSII
    LTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFL
    FSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHG
    LRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDT
    FADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYL
    CFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQ
    NELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPPHM
    NVNPQQPA

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ITPR1
  • Full Name
  • Inositol 1,4,5-trisphosphate receptor type 1
  • Introduction
  • This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
  • Alternative Names
  • ITPR1; ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; IP3 receptor; IP3R 1; inositol 1,4,5-triphosphate receptor, type 1; protein phosphatase 1, regulatory subunit 94; type 1 InsP3 receptor; type 1 inositol 1,4,5-trisphosphate receptor; Inositol 1,4,5-trisphosphate receptor type 1

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