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Magic™ Membrane Protein Human JAG2 (Jagged canonical Notch ligand 2) Expressed in CHO for Antibody Discovery, Partial (27-1082aa) (CAT#: MPX0515K)

This product is a 138.7 kDa Human JAG2 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • JAG2
  • Protein Length
  • Partial (27-1082aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 138.7 kDa
  • TMD
  • 1
  • Sequence
  • MGYFELQLSALRNVNGELLSGACC
    DGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGPCSYGHGATPVLGG
    NSFYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVEAWD
    WDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDE
    NYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCN
    LLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWG
    GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHA
    CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC
    VDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCI
    PGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERD
    ECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGAR
    CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGT
    AASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT
    CIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCAC
    DDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVA
    KNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYN
    GGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR
    CSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRD
    CSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQCLRPPCEAWGECG
    AEEPPSTPCLPRSGHLDNNCARLTLHFNRDHVPQGTTVGAICSGIRSLPA
    TRAVARDRLLVLLCDRASSGASAVEVAVSFSPARDLPDSSLIQGAAHAIV
    AAITQRGNSSLLLAVTEVKVETVVTGGSSTGL

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS and EDTA.

Target

  • Target Protein
  • JAG2
  • Full Name
  • Jagged canonical Notch ligand 2
  • Introduction
  • The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • JAG2; HJ2; SER2; protein jagged-2; jagged 2; Jagged canonical Notch ligand 2

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