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Magic™ Membrane Protein Human JPH2 (Junctophilin 2) Full Length (CAT#: MPC1058K) Made to Order

This product is a 74.2 kDa Human JPH2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • JPH2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 74.2 kDa
  • TMD
  • 1
  • Sequence
  • MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAG
    VYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSS
    SSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYG
    MAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPSPAIPRGGF
    ALSLLANAEAAARAPKGGGLFQRGALLGKLRRAESRTSVGSQRSRVSFLK
    SDLSSGASDAASTASLGEAAEGADEAAPFEADIDATTTETYMGEWKNDKR
    SGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDT
    KRRMLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEA
    AEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEILENSESLL
    EPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPG
    VSKDGLLSPGAWNGEPSGEGSRSVTPSEGAGRRSPARPATERMAIEALQA
    PPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPA
    TAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKARKTEARGLTKAGA
    KKKARKEAALAAEAEVEVEEVPNTILICMVILLNIGLAILFVHLLT

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • JPH2
  • Full Name
  • Junctophilin 2
  • Introduction
  • Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.
  • Alternative Names
  • JPH2; JP2; JP-2; CMH17; junctophilin-2; junctophilin type 2; Junctophilin-2 N-terminal fragment; JP2NT; Junctophilin 2

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