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Magic™ Membrane Protein Human KCNB2 (Potassium voltage-gated channel subfamily B member 2) Full Length (CAT#: MPC0586K) Made to Order

This product is a 102.5 kDa Human KCNB2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNB2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 102.5 kDa
  • TMD
  • 6
  • Sequence
  • MAEKAPPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLW
    RTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSIL
    NFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNE
    ELRREAETMREREGEEFDNTCCPDKRKKLWDLLEKPNSSVAAKILAIVSI
    LFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEAVCIAWFTMEYLL
    RFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVV
    QIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFS
    SLVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGL
    CCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIV
    SMNLKDAFARSMELIDVAVEKAGESANTKDSADDNHLSPSRWKWARKALS
    ETSSNKSFENKYQEVSQKDSHEQLNNTSSSSPQHLSAQKLEMLYNEITKT
    QPHSHPNPDCQEKPERPSAYEEEIEMEEVVCPQEQLAVAQTEVIVDMKST
    SSIDSFTSCATDFTETERSPLPPPSASHLQMKFPTDLPGTEEHQRARGPP
    FLTLSREKGPAARDGTLEYAPVDITVNLDASGSQCGLHSPLQSDNATDSP
    KSSLKGSNPLKSRSLKVNFKENRGSAPQTPPSTARPLPVTTADFSLTTPQ
    HISTILLEETPSQGDRPLLGTEVSAPCQGPSKGLSPRFPKQKLFPFSSRE
    RRSFTEIDTGDDEDFLELPGAREEKQVDSSPNCFADKPSDGRDPLREEGS
    VGSSSPQDTGHNCRQDIYHAVSEVKKDSSQEGCKMENHLFAPEIHSNPGD
    TGYCPTRETSM

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNB2
  • Full Name
  • Potassium voltage-gated channel subfamily B member 2
  • Introduction
  • Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells.
  • Alternative Names
  • KV2.2; potassium voltage-gated channel subfamily B member 2; delayed rectifier potassium channel protein; potassium channel Kv2.2; potassium channel, voltage gated Shab related subfamily B, member 2; potassium voltage-gated channel, Shab-related subfamily, member 2; voltage-gated potassium channel subunit Kv2.2; KCNB2; Potassium voltage-gated channel subfamily B member 2

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