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Magic™ Membrane Protein Human KCNJ4 (Potassium inwardly rectifying channel subfamily J member 4) Full Length (CAT#: MPC0611K) Made to Order

This product is a 49.5 kDa Human KCNJ4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNJ4
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 49.5 kDa
  • TMD
  • 2
  • Sequence
  • MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTC
    VDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPA
    AGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAV
    IAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKL
    CLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGL
    DRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT
    TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSA
    RELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAG
    LGLEAGSKEEAGIIRMLEFGSHLDLERMQASLPLDNISYRRESAI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNJ4
  • Full Name
  • Potassium inwardly rectifying channel subfamily J member 4
  • Introduction
  • Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
  • Alternative Names
  • HIR; HRK1; IRK3; HIRK2; IRK-3; Kir2.3; inward rectifier potassium channel 4; hippocampal inward rectifier potassium channel; inward rectifier K(+) channel Kir2.3; potassium channel, inwardly rectifying subfamily J, member 4; potassium voltage-gated channel subfamily J member 4; KCNJ4; Potassium inwardly rectifying channel subfamily J member 4

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