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Magic™ Membrane Protein Human KCNN4 (Potassium calcium-activated channel subfamily N member 4) Full Length (CAT#: MPC2360K) Made to Order

This product is a made-to-order Human KCNN4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNN4
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • TMD
  • 6
  • Sequence
  • MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFG
    GCSWALYLFLVKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVAL
    TGRQAAQIVLELVVCGLHPAPVRGPPCVQDLGAPLTSPQPWPGFLGQGEA
    LLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYM
    NTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLT
    IGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN
    FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINA
    FRQVRLKHRKLREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLA
    GKLDALTELLSTALGPRQLPEPSQQSK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • GFP tag at the C-terminus
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • KCNN4
  • Full Name
  • Potassium calcium-activated channel subfamily N member 4
  • Introduction
  • The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
  • Alternative Names
  • KCNN4; IK; IK1; SK4; DHS2; KCA4; hSK4; IKCA1; hKCa4; KCa3.1; hIKCa1; intermediate conductance calcium-activated potassium channel protein 4; SKCa 4; SKCa4; intermediate-conductance Ca2+-activated K+ channel, KCa3.1; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; putative Gardos channel; putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel; small conductance calcium-activated potassium channel 4; Potassium calcium-activated channel subfamily N member 4

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