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Magic™ Membrane Protein Human KIRREL2 (Kirre like nephrin family adhesion molecule 2) Full Length (CAT#: MPC2739K) Made to Order

This product is a made-to-order Human KIRREL2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KIRREL2
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MLRMRVPALLVLLFCFRGRAGPSPHFLQQPEDLVVLLGEEARLPCALGAY
    WGLVQWTKSGLALGGQRDLPGWSRYWISGNAANGQHDLHIRPVELEDEAS
    YECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRG
    DARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVESTLTLTPFSHDDGA
    TFVCRARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFLCQA
    TAQPPVTGYRWAKGGSPVLGARGPRLEVVADASFLTEPVSCEVSNAVGSA
    NRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLPRVTWTRRGG
    AQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPV
    VTALHSAPAFLRGPARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVE
    TFPAPESRGGLGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASL
    GRRDLLPTVRIVAGVAAATTTLLMVITGVALCCWRHSKASASFSEQKNLM
    RIPGSSDGSSSRGPEEEETGSREDRGPIVHTDHSDLVLEEKGTLETKDPT
    NGYYKVRGVSVSLSLGEAPGGGLFLPPPSPLGPPGTPTFYDFNPHLGMVP
    PCRLYRARAGYLTTPHPRAFTSYIKPTSFGPPDLAPGTPPFPYAAFPTPS
    HPRLQTHV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • KIRREL2
  • Full Name
  • Kirre like nephrin family adhesion molecule 2
  • Introduction
  • This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.
  • Alternative Names
  • KIRREL2; NLG1; NEPH3; FILTRIN; kin of IRRE-like protein 2; kin of IRRE like 2; kin of irregular chiasm-like protein 2; nephrin-like gene 1; nephrin-like protein 3; Kirre like nephrin family adhesion molecule 2

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